Across TCGA cell cohorts, RAD51D mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAD51D-associated genes across cancer lineages are CCR8, ACTRT1, and CYLC1. Each is linked with RAD51D in more than 1 cancer types. Because this analysis shows association rather than direction, both RAD51D-to-partner and partner-to-RAD51D results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD51D→partner) and Y-score (partner→RAD51D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CCR8 →	+0.022	+5.369	<.001	.004	3	2
SOFT_TISSUE	ACTRT1 →	+0.023	+5.977	<.001	.001	3	1
SOFT_TISSUE	CYLC1 →	+0.036	+4.930	<.001	.008	3	1
LARGE_INTESTINE	SLC35G3 →	+0.011	+4.467	<.001	.004	3	1
LARGE_INTESTINE	TBC1D21 →	+0.015	+5.022	<.001	.002	3	1
LARGE_INTESTINE	OR4F4 →	+0.017	+4.273	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

RAD51D survival (RNA) · tumor vs normal (RNA) · all RAD51D data types