RAD51C

Across TCGA patient cohorts, RAD51C protein abundance is significantly associated with the RNA expression of many other genes, with 10,233 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RAD51C-associated genes across cancer lineages are KPNA2, DEPDC1, and TRIP13. Each is linked with RAD51C in more than 3 cancer types. Because this analysis shows association rather than direction, both RAD51C-to-partner and partner-to-RAD51C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAD51C versus KPNA2 in OV, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD51C→partner) and Y-score (partner→RAD51C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KPNA2 →	+1.909	+1.395	<.001	.003	3	4
OV	DEPDC1 →	+2.108	+1.395	.001	.001	3	4
OV	TRIP13 →	+1.994	+1.692	.003	<.001	3	4
LUAD	SCGB1A1 →	-2.382	-0.522	.002	<.001	3	3
LSCC	INCENP →	+0.504	+0.423	<.001	<.001	3	3
LSCC	JARID2 →	+0.484	+0.383	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,233 associations by consensus.

RAD51C vs KPNA2 — OV

Explore this scatter interactively →