RAD23B

Across TCGA patient cohorts, RAD23B mutation is significantly associated with the RNA expression of many other genes, with 1,304 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAD23B-associated genes across cancer lineages are RNA5SP413, RNA5SP422, and MIR3619. Each is linked with RAD23B in more than 1 cancer types. Because this analysis shows association rather than direction, both RAD23B-to-partner and partner-to-RAD23B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP413 grouped by RAD23B-low versus RAD23B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD23B→partner) and Y-score (partner→RAD23B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP413 →	+0.960	+1.829	<.001	.001	3	2
UCEC	RNA5SP422 →	+0.713	+1.993	<.001	.001	3	2
SKCM	MIR3619 →	+0.511	+4.765	<.001	.003	3	2
COAD	MIR588 →	+0.323	+4.418	<.001	.008	3	2
COAD	RN7SL22P →	+0.244	+4.374	<.001	.002	3	2
BRCA	H2AB2 →	+0.124	+9.057	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,304 associations by consensus.

RNA5SP413 by RAD23B expression — UCEC

Explore this box plot interactively →