Across TCGA pan-cancer cohorts, RAD23A Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RAD23A data layer compared with 27 for mass-spec protein and 5 for mass-spec protein.
The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher RAD23A Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAD23A expression acts as an unfavorable survival marker.
OV, UCEC, and ACC are the cancer types where RAD23A Mutation most reproducibly stratifies survival.