RAD23A

Across TCGA pan-cancer cohorts, RAD23A mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RAD23A data layer compared with 27 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RAD23A mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated RAD23A expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, HNSC, and LUAD are the cancer types where RAD23A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	IV	0.785	0.123	.009	23	view →
HNSC	OS	Quartile	All	0.761	0.930	.015	15	view →
LUAD	DFS	Tertile	II,III,IV	0.380	0.793	.033	9	view →
LSCC	OS	Quartile	III,IV	0.570	1.000	.048	7	view →
PDAC	DFS	Median	II,III,IV	0.824	0.641	.014	7	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RAD23A–CCRCC (OS)

Open the CCRCC breakdown →