RAD23A

Across TCGA patient cohorts, RAD23A mutation is significantly associated with the RNA expression of many other genes, with 367 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAD23A-associated genes across cancer lineages are MIR509-2, RNU6-947P, and ACTR3BP6. Each is linked with RAD23A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAD23A-to-partner and partner-to-RAD23A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR509-2 grouped by RAD23A-low versus RAD23A-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD23A→partner) and Y-score (partner→RAD23A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR509-2 →	+0.260	+6.466	<.001	<.001	3	2
STAD	RNU6-947P →	+0.468	+5.026	<.001	.009	3	2
STAD	ACTR3BP6 →	+0.037	+5.187	<.001	.007	3	2
SKCM	OR1B1 →	+0.036	+5.039	<.001	.003	3	2
SKCM	OR56A1 →	+0.035	+4.282	<.001	.009	3	2
SKCM	SNORD116-23 →	+0.342	+4.508	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 367 associations by consensus.

MIR509-2 by RAD23A expression — BLCA

Explore this box plot interactively →