RAD23A

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RAD23A mutation is significantly associated with the drug of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAD23A-associated genes across cancer lineages are PD0325901, CCT007093, and 50869. Each is linked with RAD23A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAD23A-to-partner and partner-to-RAD23A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PD0325901 grouped by RAD23A-low versus RAD23A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD23A→partner) and Y-score (partner→RAD23A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEPD0325901 →-0.535-2.745.034.04731
LARGE_INTESTINECCT007093 →+0.348+2.649.019.04631
LARGE_INTESTINE50869 →+0.479+2.871.016.02131
LARGE_INTESTINEAra-G →+0.169+2.944.034.01831
LARGE_INTESTINEETP-45835 →+0.277+2.874.014.02131
LARGE_INTESTINEEg5_9814 →+0.783+2.807.003.03521
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

PD0325901 by RAD23A expression — LARGE_INTESTINE

Box plot of PD0325901 in RAD23A-low vs RAD23A-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration