Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts
Across TCGA cell cohorts, RAD23A mutation is significantly associated with the drug of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.
The most reproducible RAD23A-associated genes across cancer lineages are PD0325901, CCT007093, and 50869. Each is linked with RAD23A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAD23A-to-partner and partner-to-RAD23A results are reported.
Each partner links to its own Q-omics profile. The box plot shows the strongest example, PD0325901 grouped by RAD23A-low versus RAD23A-high in LARGE_INTESTINE.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (RAD23A→partner) and Y-score (partner→RAD23A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.