RAD21-AS1

Across TCGA pan-cancer cohorts, RAD21-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RAD21-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RAD21-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAD21-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SKCM show a favorable association.

KICH, KIRP, and KIRC are the cancer types where RAD21-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	II,III,IV	0.556	0.957	.001	47	view →
KIRP	DFS	Median	All	0.782	0.945	<.001	43	view →
KIRC	DFS	Median	All	0.692	0.562	.002	34	view →
SKCM	OS	Tertile	All	0.541	0.229	<.001	33	view →
ACC	DFS	Median	III,IV	0.590	0.148	.001	31	view →
UCS	DFS	Median	IV	0.850	0.475	.023	24	view →
LGG	DFS	Quartile	All	0.655	0.387	<.001	22	view →
UVM	DFS	Median	III,IV	0.284	0.907	.002	21	view →
READ	DFS	Tertile	IV	0.315	0.806	.007	19	view →
CESC	DFS	Quartile	III,IV	0.278	0.780	.028	16	view →
ESCA	DFS	Quartile	III,IV	0.563	0.213	.023	12	view →
CHOL	DFS	Tertile	All	0.644	0.183	.002	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RAD21-AS1–KICH (DFS)

Open the KICH breakdown →