Across TCGA patient cohorts, RACK1 mutation is significantly associated with the RNA expression of many other genes, with 1,257 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RACK1-associated genes across cancer lineages are OR4C9P, MRPS5P4, and SERPINB8P1. Each is linked with RACK1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RACK1-to-partner and partner-to-RACK1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RACK1→partner) and Y-score (partner→RACK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OR4C9P →	+0.060	+6.608	<.001	.001	3	3
SKCM	MRPS5P4 →	+0.069	+6.495	<.001	<.001	3	2
HNSC	SERPINB8P1 →	+0.143	+6.936	<.001	<.001	3	2
HNSC	LINC01626 →	+0.204	+5.578	<.001	.004	3	2
LIHC	MIR3661 →	+0.350	+5.268	<.001	.006	3	2
LIHC	GLUD1P4 →	+0.097	+5.878	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,257 associations by consensus.

Exploration

RACK1 survival (RNA) · tumor vs normal (RNA) · all RACK1 data types