Across TCGA cell cohorts, RACK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,012 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible RACK1-associated GO terms across cancer lineages are tRNA 5'-end processing, Mitochondrial disulfide relay system, and Protein import into mitochondrial intermembrane space. Each is linked with RACK1 in more than 9 cancer types. Because this analysis shows association rather than direction, both RACK1-to-partner and partner-to-RACK1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RACK1→partner) and Y-score (partner→RACK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	tRNA 5'-end processing →	+0.128	+0.903	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Mitochondrial disulfide relay system →	+0.148	+0.616	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Protein import into mitochondrial intermembrane space →	+0.153	+0.978	<.001	<.001	3	10
OVARY	Transcription initiation at mitochondrial promoter →	+0.112	+0.673	.003	<.001	3	10
STOMACH	Demethylation →	+0.109	+0.504	.005	.003	3	9
URINARY_TRACT	Dicarboxylic acid biosynthetic process →	+0.148	+0.570	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,012 associations by consensus.

Exploration

RACK1 survival (RNA) · tumor vs normal (RNA) · all RACK1 data types