RAC1

Across TCGA cell cohorts, RAC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,254 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RAC1-associated GO terms across cancer lineages are Positive regulation of triglyceride catabolic process, Meiotic attachment of telomere to nuclear envelope, and Meiotic telomere tethering at nuclear periphery. Each is linked with RAC1 in more than 11 cancer types. Because this analysis shows association rather than direction, both RAC1-to-partner and partner-to-RAC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of triglyceride catabolic process grouped by RAC1-low versus RAC1-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAC1→partner) and Y-score (partner→RAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Positive regulation of triglyceride catabolic process →	+0.147	+0.568	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Meiotic attachment of telomere to nuclear envelope →	+0.082	+0.566	.003	.003	3	11
UPPER_AERODIGESTIVE_TRACT	Meiotic telomere tethering at nuclear periphery →	+0.082	+0.566	.003	.003	3	11
UPPER_AERODIGESTIVE_TRACT	Meiotic telomere clustering →	+0.082	+0.566	.003	.003	3	11
LUNG_NSCLC_LUSC	Positive regulation of substrate adhesion-dependent cell spreading →	+0.111	+0.785	.009	.006	3	10
PANCREAS	Maintenance of unfolded protein →	+0.140	+0.534	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,254 associations by consensus.

Positive regulation of triglyceride catabolic process by RAC1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →