RABL2B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RABL2B mutation is significantly associated with the RNA expression of many other genes, with 177 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RABL2B-associated genes across cancer lineages are RN7SL134P, RNA5SP412, and RNA5SP413. Each is linked with RABL2B in more than 1 cancer types. Because this analysis shows association rather than direction, both RABL2B-to-partner and partner-to-RABL2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by RABL2B-low versus RABL2B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABL2B→partner) and Y-score (partner→RABL2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL134P →+0.121+3.236.002<.00132
UCECRNA5SP412 →+0.820+2.604<.001<.00132
UCECRNA5SP413 →+1.827+3.414<.001<.00132
BRCAMIR8080 →+0.457+8.471<.001.00531
BRCAMIR6846 →+0.361+8.055<.001.00731
UCECMIR3912 →+0.204+2.500.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 177 associations by consensus.

RN7SL134P by RABL2B expression — UCEC

Box plot of RN7SL134P in RABL2B-low vs RABL2B-high samples in UCEC.

Explore this box plot interactively →

Exploration