RABL2B

Across TCGA patient cohorts, RABL2B mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RABL2B-associated genes across cancer lineages are JNK2, Ku80, and PDK1_pS241. Each is linked with RABL2B in more than 1 cancer types. Because this analysis shows association rather than direction, both RABL2B-to-partner and partner-to-RABL2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by RABL2B-low versus RABL2B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABL2B→partner) and Y-score (partner→RABL2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.374	+3.026	<.001	.018	3	1
UCEC	Ku80 →	+0.270	+2.183	.018	.033	3	1
UCEC	PDK1_pS241 →	+0.273	+2.472	<.001	.011	3	1
UCEC	Tuberin →	+0.439	+3.584	<.001	.002	3	1
UCEC	Di-Ras3 →	-0.207	-3.156	.003	.018	3	1
UCEC	Heregulin →	-0.202	-3.459	<.001	.005	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

JNK2 by RABL2B expression — UCEC

Explore this box plot interactively →