RABL2A

Across TCGA patient cohorts, RABL2A mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RABL2A-associated genes across cancer lineages are JNK2, PCNA, and Syk. Each is linked with RABL2A in more than 1 cancer types. Because this analysis shows association rather than direction, both RABL2A-to-partner and partner-to-RABL2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by RABL2A-low versus RABL2A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABL2A→partner) and Y-score (partner→RABL2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.252	+3.169	.020	.020	3	1
UCEC	PCNA →	+0.362	+3.169	.002	.020	3	1
UCEC	Syk →	+0.516	+3.183	.012	.010	3	1
UCEC	Tuberin →	+0.292	+3.009	.048	.019	3	1
UCEC	eIF4G →	+0.411	+3.169	.015	.020	1	1
UCEC	MEK1 →	+0.477	+3.169	.017	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

JNK2 by RABL2A expression — UCEC

Explore this box plot interactively →