RABL2A

Across TCGA pan-cancer cohorts, RABL2A RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of RABL2A’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RABL2A RNA is repressed in tumor relative to normal tissue. In most cancer types RABL2A is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, LIHC, and THCA are the cancer types where RABL2A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RABL2A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−1.614	<.001	9	view →
LIHC	All	All	+0.387	<.001	7	view →
THCA	All	All	−0.382	<.001	6	view →
CHOL	All	All	+1.897	<.001	5	view →
KIRP	All	IV	+0.717	.006	5	view →
LUAD	All	All	−0.346	.005	5	view →
KIRC	All	All	+0.254	<.001	4	view →
READ	Female	All	+0.432	.024	3	view →
UCEC	All	All	−0.560	.035	2	view →
STAD	All	II,III,IV	+0.330	.034	2	view →
COAD	All	IV	+0.251	.040	2	view →
BLCA	Male	IV	−0.650	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

RABL2A–KICH

Open the KICH breakdown →