RABGGTB

Across TCGA cell cohorts, RABGGTB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,233 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RABGGTB-associated GO terms across cancer lineages are Positive regulation of rRNA processing, Positive regulation of translational elongation, and IMP biosynthetic process. Each is linked with RABGGTB in more than 12 cancer types. Because this analysis shows association rather than direction, both RABGGTB-to-partner and partner-to-RABGGTB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of rRNA processing grouped by RABGGTB-low versus RABGGTB-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RABGGTB→partner) and Y-score (partner→RABGGTB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Positive regulation of rRNA processing →	+0.121	+0.708	<.001	.008	3	13
BLOOD_Leukemia	Positive regulation of translational elongation →	+0.098	+0.463	<.001	.007	2	12
LARGE_INTESTINE	IMP biosynthetic process →	+0.150	+1.026	<.001	<.001	3	11
CNS	Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.108	+0.846	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of centriole replication →	+0.102	+0.832	<.001	<.001	3	10
LARGE_INTESTINE	'de novo' IMP biosynthetic process →	+0.149	+1.177	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,233 associations by consensus.

Positive regulation of rRNA processing by RABGGTB expression — LARGE_INTESTINE

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