RABGGTB

Across TCGA cell cohorts, RABGGTB mutation is significantly associated with the RNA expression of many other genes, with 166 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RABGGTB-associated genes across cancer lineages are GKN1, OR52E4, and ZCCHC13. Each is linked with RABGGTB in more than 1 cancer types. Because this analysis shows association rather than direction, both RABGGTB-to-partner and partner-to-RABGGTB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GKN1 grouped by RABGGTB-low versus RABGGTB-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABGGTB→partner) and Y-score (partner→RABGGTB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GKN1 →	+0.068	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR52E4 →	+0.015	+5.201	<.001	.006	3	1
BLOOD_Leukemia	ZCCHC13 →	+0.030	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	GRXCR1 →	+0.023	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	OR11H2 →	+0.074	+5.201	<.001	.006	3	1
LARGE_INTESTINE	ZBED4 →	+0.570	+3.212	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 166 associations by consensus.

GKN1 by RABGGTB expression — BLOOD_Leukemia

Explore this box plot interactively →