RABGGTA

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RABGGTA protein abundance is significantly associated with the RNA expression of many other genes, with 15,878 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RABGGTA-associated genes across cancer lineages are POLA1, THADA, and MSH6. Each is linked with RABGGTA in more than 4 cancer types. Because this analysis shows association rather than direction, both RABGGTA-to-partner and partner-to-RABGGTA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RABGGTA versus POLA1 in LSCC, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABGGTA→partner) and Y-score (partner→RABGGTA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCPOLA1 →-0.718-0.166<.001<.00135
LSCCTHADA →-0.347-0.162<.001<.00135
LSCCMSH6 →-0.855-0.231<.001<.00135
LSCCRPIA →-0.626-0.139<.001<.00135
LSCCTMEM116 →-0.843-0.174<.001<.00135
HNSCANKRD22 →+1.124+0.306<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,878 associations by consensus.

RABGGTA vs POLA1 — LSCC

Per-sample scatter of RABGGTA vs POLA1 in LSCC (Pearson r = -0.50).

Explore this scatter interactively →

Exploration