RABGGTA

Across TCGA patient cohorts, RABGGTA mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RABGGTA-associated genes across cancer lineages are FoxM1, Shc_pY317, and JNK_pT183_Y185. Each is linked with RABGGTA in more than 1 cancer types. Because this analysis shows association rather than direction, both RABGGTA-to-partner and partner-to-RABGGTA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by RABGGTA-low versus RABGGTA-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABGGTA→partner) and Y-score (partner→RABGGTA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.261	+1.906	.012	.016	3	2
UCEC	Shc_pY317 →	-0.185	-2.000	.002	.030	3	2
UCEC	JNK_pT183_Y185 →	-0.168	-2.401	.013	.003	3	1
UCEC	JNK2 →	+0.187	+2.125	.019	.010	3	1
UCEC	LKB1 →	-0.096	-3.169	.025	.019	3	1
UCEC	MEK1 →	+0.407	+1.906	.005	.016	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

FoxM1 by RABGGTA expression — UCEC

Explore this box plot interactively →