RABGEF1

Across TCGA patient cohorts, RABGEF1 mutation is significantly associated with the RNA expression of many other genes, with 1,217 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RABGEF1-associated genes across cancer lineages are RNU7-193P, WSPAR, and RNU6-492P. Each is linked with RABGEF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RABGEF1-to-partner and partner-to-RABGEF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-193P grouped by RABGEF1-low versus RABGEF1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABGEF1→partner) and Y-score (partner→RABGEF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU7-193P →	+0.978	+4.418	<.001	.008	3	3
CESC	WSPAR →	+0.082	+4.539	<.001	.001	3	2
HNSC	RNU6-492P →	+0.478	+7.954	<.001	.008	3	2
CESC	KRT18P49 →	+0.136	+3.759	<.001	.006	3	2
LUAD	RNU5E-4P →	+0.695	+3.822	.006	.009	3	2
LUAD	MIR181A1 →	+0.365	+4.928	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,217 associations by consensus.

RNU7-193P by RABGEF1 expression — COAD

Explore this box plot interactively →