RABGAP1L

Across TCGA cell cohorts, RABGAP1L mutation is significantly associated with the mutation status of many other genes, with 5,142 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RABGAP1L-associated genes across cancer lineages are USP34, SATB2, and SCN4A. Each is linked with RABGAP1L in more than 5 cancer types. Because this analysis shows association rather than direction, both RABGAP1L-to-partner and partner-to-RABGAP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP34 grouped by RABGAP1L-low versus RABGAP1L-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABGAP1L→partner) and Y-score (partner→RABGAP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	USP34 →	+3.647	+4.337	<.001	<.001	1	6
OVARY	SATB2 →	+4.217	+4.217	.001	.001	1	5
BLOOD_Lymphoma	SCN4A →	+3.232	+3.523	.006	.006	1	5
LARGE_INTESTINE	BRCA2 →	+2.273	+4.718	<.001	<.001	1	5
LUNG_NSCLC_LUAD	AATK →	+3.000	+3.662	.007	.007	1	5
LARGE_INTESTINE	ANK1 →	+2.925	+2.925	<.001	<.001	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,142 associations by consensus.

USP34 by RABGAP1L expression — BLOOD_Lymphoma

Explore this box plot interactively →