RABGAP1L-IT1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RABGAP1L-IT1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RABGAP1L-IT1 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RABGAP1L-IT1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RABGAP1L-IT1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and BLCA show a favorable association.

BRCA, KIRC, and HNSC are the cancer types where RABGAP1L-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSQuartileII,III,IV0.9850.948.00187view →
KIRCOSMedianAll0.5010.709<.00179view →
HNSCDFSTertileII,III,IV0.1380.430<.00171view →
THCAOSTertileIII,IV0.9010.994<.00151view →
ACCDFSTertileIV0.0100.383<.00145view →
BLCAOSQuartileIII,IV0.5460.273.00231view →
UVMOSTertileIII,IV0.1780.933<.00127view →
MESOOSTertileIV0.0770.592.01927view →
CESCDFSMedianIV0.7380.327.01424view →
ESCAOSMedianAll0.6591.000.02018view →
OVOSQuartileAll0.4300.263<.00118view →
CHOLOSTertileIII,IV0.2750.886.04518view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

Exploration