RABGAP1

Across TCGA pan-cancer cohorts, RABGAP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RABGAP1 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RABGAP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RABGAP1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, HNSC, and UCEC are the cancer types where RABGAP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	II,III,IV	0.838	0.452	.002	46	view →
HNSC	DFS	Tertile	II,III,IV	0.911	0.663	.005	45	view →
UCEC	DFS	Tertile	III,IV	0.482	1.000	.042	16	view →
PDAC	OS	Quartile	II,III,IV	0.701	1.000	.022	3	view →
GBM	DFS	Quartile	All	0.792	0.580	.018	1	view →
LUAD	OS	Quartile	All	0.751	1.000	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RABGAP1–CCRCC (DFS)

Open the CCRCC breakdown →