RABGAP1

Across TCGA cell cohorts, RABGAP1 mutation is significantly associated with the RNA expression of many other genes, with 85 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RABGAP1-associated genes across cancer lineages are STOML3, OR52K1, and PPDPFL. Each is linked with RABGAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RABGAP1-to-partner and partner-to-RABGAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STOML3 grouped by RABGAP1-low versus RABGAP1-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RABGAP1→partner) and Y-score (partner→RABGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	STOML3 →	+0.006	+4.807	<.001	.006	3	1
BLOOD_Lymphoma	OR52K1 →	+0.009	+4.169	<.001	.002	3	1
STOMACH	PPDPFL →	+1.596	+4.129	<.001	.007	3	1
BREAST	OR10W1 →	+0.010	+4.781	<.001	.003	3	1
CNS	CCL1 →	+0.504	+4.472	<.001	.004	3	1
BLOOD_Leukemia	ASZ1 →	+0.145	+4.152	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 85 associations by consensus.

STOML3 by RABGAP1 expression — BLOOD_Myeloma

Explore this box plot interactively →