RABEP1

Across TCGA pan-cancer cohorts, RABEP1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated RABEP1 data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RABEP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RABEP1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

COAD, PDAC, and CCRCC are the cancer types where RABEP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.915	1.000	.009	36	view →
PDAC	OS	Median	III,IV	0.576	0.278	.004	27	view →
CCRCC	OS	Median	All	1.000	0.898	.008	17	view →
UCEC	OS	Tertile	II,III,IV	0.553	1.000	.018	14	view →
LUAD	DFS	Median	All	0.746	0.492	.011	12	view →
GBM	DFS	Quartile	All	0.757	0.547	.036	1	view →
HNSC	DFS	Tertile	III,IV	0.504	0.749	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RABEP1–COAD (DFS)

Open the COAD breakdown →