RAB9B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RAB9B mutation is significantly associated with the RNA expression of many other genes, with 703 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB9B-associated genes across cancer lineages are TRAJ57, RNU6-452P, and MIR802. Each is linked with RAB9B in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB9B-to-partner and partner-to-RAB9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ57 grouped by RAB9B-low versus RAB9B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB9B→partner) and Y-score (partner→RAB9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTRAJ57 →+0.532+2.470<.001.00532
SKCMRNU6-452P →+0.286+7.816<.001.00831
SKCMMIR802 →+0.323+7.816<.001.00831
SKCMMIR876 →+0.363+7.816<.001.00831
UCECFBXO7 →+0.429+3.362.008.00531
UCECPOLDIP3 →+0.503+3.362.009.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 703 associations by consensus.

TRAJ57 by RAB9B expression — UCEC

Box plot of TRAJ57 in RAB9B-low vs RAB9B-high samples in UCEC.

Explore this box plot interactively →

Exploration