RAB9A

Across TCGA patient cohorts, RAB9A mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB9A-associated genes across cancer lineages are EGFR_pY1068, FASN, and Notch1. Each is linked with RAB9A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB9A-to-partner and partner-to-RAB9A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by RAB9A-low versus RAB9A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB9A→partner) and Y-score (partner→RAB9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.266	-2.115	.015	.019	3	1
UCEC	FASN →	+0.364	+2.115	.034	.019	3	1
UCEC	Notch1 →	+0.237	+2.472	<.001	.010	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.443	-2.321	.024	.034	3	1
UCEC	Rad50 →	-0.296	-2.807	.005	.003	3	1
UCEC	RAD51 →	+0.147	+2.321	.016	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

EGFR_pY1068 by RAB9A expression — UCEC

Explore this box plot interactively →