RAB8B

Across TCGA cell cohorts, RAB8B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,292 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAB8B-associated GO terms across cancer lineages are Regulation of corticotropin secretion, Positive regulation of corticotropin secretion, and Protein import into peroxisome membrane. Each is linked with RAB8B in more than 19 cancer types. Because this analysis shows association rather than direction, both RAB8B-to-partner and partner-to-RAB8B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of corticotropin secretion grouped by RAB8B-low versus RAB8B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB8B→partner) and Y-score (partner→RAB8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of corticotropin secretion →	+1.782	+1.692	<.001	<.001	3	20
LUNG_NSCLC_LUSC	Positive regulation of corticotropin secretion →	+1.516	+1.855	<.001	<.001	3	20
OESOPHAGUS	Protein import into peroxisome membrane →	+0.189	+1.403	<.001	<.001	3	19
STOMACH	Vesicle cargo loading →	+0.131	+1.456	<.001	.001	3	15
BONE	Vesicle-mediated transport to the plasma membrane →	+0.063	+1.079	<.001	<.001	3	13
OESOPHAGUS	Regulation of hippo signaling →	+0.092	+1.098	.006	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,292 associations by consensus.

Regulation of corticotropin secretion by RAB8B expression — BONE

Explore this box plot interactively →