RAB8A

Across TCGA patient cohorts, RAB8A mutation is significantly associated with the RNA expression of many other genes, with 1,060 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB8A-associated genes across cancer lineages are RNU1-17P, RNU6-1211P, and RNA5SP432. Each is linked with RAB8A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB8A-to-partner and partner-to-RAB8A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by RAB8A-low versus RAB8A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB8A→partner) and Y-score (partner→RAB8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU1-17P →	+0.170	+2.257	.002	.006	3	2
LUAD	RNU6-1211P →	+0.192	+7.930	<.001	.008	3	2
SKCM	RNA5SP432 →	+0.641	+5.118	<.001	.001	3	2
BLCA	RN7SL147P →	+0.209	+5.177	.001	.007	3	2
BLCA	KRTAP12-1 →	+0.115	+5.588	<.001	.004	3	1
BLCA	RNU5F-3P →	+0.379	+5.788	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,060 associations by consensus.

RNU1-17P by RAB8A expression — UCEC

Explore this box plot interactively →