RAB7B

Across TCGA cell cohorts, RAB7B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,486 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RAB7B-associated GO terms across cancer lineages are Late endosome to Golgi transport, Negative regulation of amino acid metabolic process, and Negative regulation of amino acid biosynthetic process. Each is linked with RAB7B in more than 10 cancer types. Because this analysis shows association rather than direction, both RAB7B-to-partner and partner-to-RAB7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Late endosome to Golgi transport grouped by RAB7B-low versus RAB7B-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB7B→partner) and Y-score (partner→RAB7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Late endosome to Golgi transport →	-0.171	-1.101	.003	.006	3	11
LIVER	Negative regulation of amino acid metabolic process →	+0.401	+1.697	<.001	<.001	3	11
LIVER	Negative regulation of amino acid biosynthetic process →	+0.401	+1.697	<.001	<.001	3	11
BONE	Viral process →	+0.085	+1.580	<.001	<.001	3	10
LIVER	Positive regulation of intracellular transport →	+0.067	+1.438	.001	.008	2	11
SOFT_TISSUE	Gliogenesis →	+0.057	+0.941	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,486 associations by consensus.

Late endosome to Golgi transport by RAB7B expression — KIDNEY

Explore this box plot interactively →