RAB5IF

Across TCGA patient cohorts, RAB5IF mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB5IF-associated genes across cancer lineages are LINC01173, RNU6-1313P, and RNU6-340P. Each is linked with RAB5IF in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB5IF-to-partner and partner-to-RAB5IF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01173 grouped by RAB5IF-low versus RAB5IF-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB5IF→partner) and Y-score (partner→RAB5IF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01173 →	+0.388	+3.169	.001	.006	3	1
COAD	RNU6-1313P →	+0.593	+7.741	<.001	.009	3	1
COAD	RNU6-340P →	+0.363	+7.741	<.001	.009	3	1
COAD	RNU6-533P →	+0.571	+7.741	<.001	.009	3	1
UCEC	GYG2P1 →	+0.054	+3.063	<.001	.008	3	1
UCEC	RNU6-519P →	+0.725	+3.315	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

LINC01173 by RAB5IF expression — UCEC

Explore this box plot interactively →