RAB5A

Across TCGA patient cohorts, RAB5A RNA expression is significantly associated with the protein abundance of many other proteins, with 10,210 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible RAB5A-associated proteins across cancer lineages are DYNC1LI1, PDCD6IP, and MKRN2. Each is linked with RAB5A in more than 5 cancer types. Because this analysis shows association rather than direction, both RAB5A-to-partner and partner-to-RAB5A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAB5A versus DYNC1LI1 in HNSC, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB5A→partner) and Y-score (partner→RAB5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DYNC1LI1 →	+0.253	+0.527	<.001	<.001	3	6
PDAC	PDCD6IP →	+0.311	+0.332	<.001	<.001	3	5
PDAC	MKRN2 →	+0.203	+0.218	<.001	.001	3	4
COAD	DENND1A_S592 →	-0.405	-0.280	.003	.002	3	4
PDAC	TSG101 →	+0.180	+0.231	<.001	<.001	3	3
OV	UBP1 →	+0.295	+0.354	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,210 associations by consensus.

RAB5A vs DYNC1LI1 — HNSC

Explore this scatter interactively →