RAB5A

Across TCGA patient cohorts, RAB5A mutation is significantly associated with the RNA expression of many other genes, with 3,946 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB5A-associated genes across cancer lineages are RNA5SP413, RN7SL763P, and RNU6-463P. Each is linked with RAB5A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB5A-to-partner and partner-to-RAB5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP413 grouped by RAB5A-low versus RAB5A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB5A→partner) and Y-score (partner→RAB5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP413 →	+0.773	+1.692	<.001	.004	3	2
COAD	RN7SL763P →	+0.345	+6.977	<.001	<.001	3	2
HNSC	RNU6-463P →	+0.363	+7.954	<.001	.008	3	1
HNSC	RNA5SP176 →	+0.323	+7.954	<.001	.008	3	1
BLCA	NCSTNP1 →	+0.283	+7.640	<.001	.009	3	1
UCEC	IGHV3OR16-13 →	+0.446	+2.218	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,946 associations by consensus.

RNA5SP413 by RAB5A expression — UCEC

Explore this box plot interactively →