RAB4B

Across TCGA patient cohorts, RAB4B mutation is significantly associated with the RNA expression of many other genes, with 894 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB4B-associated genes across cancer lineages are RN7SKP295, SNORD116-5, and MIR4510. Each is linked with RAB4B in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB4B-to-partner and partner-to-RAB4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP295 grouped by RAB4B-low versus RAB4B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB4B→partner) and Y-score (partner→RAB4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP295 →	+0.300	+2.782	<.001	.004	3	2
BLCA	SNORD116-5 →	+0.298	+7.640	<.001	.009	3	2
UCEC	MIR4510 →	+0.216	+3.453	<.001	.003	3	2
BLCA	OR8K4P →	+0.074	+7.640	<.001	.009	3	1
BLCA	LINC02729 →	+0.059	+7.640	<.001	.009	3	1
BLCA	MIR548X2 →	+0.887	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 894 associations by consensus.

RN7SKP295 by RAB4B expression — UCEC

Explore this box plot interactively →