RAB4B

Across TCGA pan-cancer cohorts, RAB4B RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated RAB4B data layer compared with 5 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RAB4B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RAB4B expression acts as an unfavorable survival marker, although some lineages such as CESC and HNSC show a favorable association.

KIRC, CESC, and HNSC are the cancer types where RAB4B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.548	0.707	<.001	154	view →
CESC	OS	Tertile	All	0.936	0.796	.002	80	view →
HNSC	DFS	Median	All	0.767	0.653	.001	77	view →
BLCA	OS	Tertile	All	0.774	0.621	<.001	70	view →
ACC	DFS	Quartile	All	0.086	0.778	<.001	57	view →
UVM	OS	Median	All	0.414	0.813	<.001	48	view →
PAAD	OS	Tertile	All	0.522	0.222	<.001	46	view →
LGG	OS	Tertile	All	0.338	0.529	<.001	39	view →
UCS	OS	Tertile	II,III,IV	0.396	0.776	.017	30	view →
SCLC	DFS	Quartile	All	0.797	0.362	.001	26	view →
LAML	DFS	Tertile	All	0.259	0.593	.012	24	view →
BRCA	OS	Tertile	II,III,IV	0.663	0.578	.003	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

RAB4B–KIRC (OS)

Open the KIRC breakdown →