RAB4B

Across TCGA cell cohorts, RAB4B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,646 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RAB4B-associated GO terms across cancer lineages are Rab protein signal transduction, Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), and Early endosome to Golgi transport. Each is linked with RAB4B in more than 15 cancer types. Because this analysis shows association rather than direction, both RAB4B-to-partner and partner-to-RAB4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rab protein signal transduction grouped by RAB4B-low versus RAB4B-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB4B→partner) and Y-score (partner→RAB4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Rab protein signal transduction →	+0.174	+1.047	<.001	.002	2	16
BONE	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.115	-0.899	<.001	<.001	3	14
KIDNEY	Early endosome to Golgi transport →	+0.127	+0.611	<.001	.001	3	13
BONE	Maturation of LSU-rRNA →	-0.186	-1.162	<.001	<.001	3	13
BONE	'de novo' IMP biosynthetic process →	-0.166	-1.035	<.001	<.001	3	13
BONE	Maturation of SSU-rRNA →	-0.139	-1.005	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,646 associations by consensus.

Rab protein signal transduction by RAB4B expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →