RAB41

Across TCGA patient cohorts, RAB41 mutation is significantly associated with the RNA expression of many other genes, with 371 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB41-associated genes across cancer lineages are SEPTIN7P4, IGHD1-20, and SNORD114-7. Each is linked with RAB41 in more than 2 cancer types. Because this analysis shows association rather than direction, both RAB41-to-partner and partner-to-RAB41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEPTIN7P4 grouped by RAB41-low versus RAB41-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB41→partner) and Y-score (partner→RAB41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SEPTIN7P4 →	+0.079	+4.712	.006	.007	3	3
SKCM	IGHD1-20 →	+1.298	+4.118	<.001	.004	3	2
UCEC	SNORD114-7 →	+0.216	+3.877	.004	.001	3	2
HNSC	RPL12P3 →	+0.190	+5.505	<.001	.004	3	2
HNSC	RNU7-176P →	+0.566	+5.015	.002	.009	3	2
HNSC	RNU1-143P →	+0.760	+5.505	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 371 associations by consensus.

SEPTIN7P4 by RAB41 expression — LUAD

Explore this box plot interactively →