RAB41

Across TCGA pan-cancer cohorts, RAB41 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of RAB41’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where RAB41 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RAB41 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

LIHC, THCA, and LUSC are the cancer types where RAB41 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAB41 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	+0.550	<.001	8	view →
THCA	Male	All	−0.401	<.001	8	view →
LUSC	Male	All	−0.451	<.001	7	view →
HNSC	All	All	+0.218	.002	7	view →
UCEC	All	All	−0.596	<.001	4	view →
BRCA	Female	All	−0.168	.001	4	view →
CHOL	All	All	+0.867	<.001	3	view →
KICH	All	All	−0.365	<.001	3	view →
BLCA	All	IV	−0.467	.008	2	view →
PRAD	All	All	−0.142	.035	2	view →
COAD	Female	II,III,IV	−0.211	.014	1	view →
KIRC	All	All	−0.114	.017	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

RAB41–LIHC

Open the LIHC breakdown →