RAB41

Across TCGA cell cohorts, RAB41 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,733 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAB41-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Regulation of cell cycle G1/S phase transition, and Positive regulation of DNA-templated transcription initiation. Each is linked with RAB41 in more than 11 cancer types. Because this analysis shows association rather than direction, both RAB41-to-partner and partner-to-RAB41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by RAB41-low versus RAB41-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB41→partner) and Y-score (partner→RAB41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.153	+0.203	<.001	<.001	3	12
SKIN	Regulation of cell cycle G1/S phase transition →	+0.060	+0.182	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA-templated transcription initiation →	+0.080	+0.179	<.001	<.001	3	10
BLOOD_Leukemia	Negative regulation of organelle assembly →	+0.069	+0.191	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA-templated transcription initiation →	+0.064	+0.199	.001	<.001	3	9
STOMACH	Spindle midzone assembly →	+0.189	+0.209	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,733 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by RAB41 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →