Across TCGA pan-cancer cohorts, RAB40C mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RAB40C data layer compared with 17 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RAB40C mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RAB40C expression acts as an unfavorable survival marker, although some lineages such as GBM and LUAD show a favorable association.

CCRCC, GBM, and LUAD are the cancer types where RAB40C mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.632	1.000	.010	19	view →
GBM	OS	Tertile	All	0.947	0.709	.003	9	view →
LUAD	OS	Median	III,IV	1.000	0.354	.026	6	view →
UCEC	DFS	Median	II,III,IV	1.000	0.538	.049	4	view →
HNSC	OS	Tertile	All	1.000	0.949	.046	4	view →
LSCC	OS	Median	All	0.898	1.000	.030	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: RAB40C tumor-vs-normal RNA expression · all RAB40C data types