RAB40B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RAB40B mutation is significantly associated with the RNA expression of many other genes, with 1,039 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB40B-associated genes across cancer lineages are RNA5SP509, MIR6803, and RNA5SP419. Each is linked with RAB40B in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB40B-to-partner and partner-to-RAB40B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP509 grouped by RAB40B-low versus RAB40B-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB40B→partner) and Y-score (partner→RAB40B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCRNA5SP509 →+0.373+7.924<.001.00832
UCECMIR6803 →+0.137+4.308<.001.00332
UCECRNA5SP419 →+0.463+2.183.003.00232
SKCMMIR4472-1 →+0.272+4.993<.001.00231
UCECYTHDF3-AS1 →+0.680+2.724<.001.00331
UCECCCL5 →+1.063+2.021.002.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,039 associations by consensus.

RNA5SP509 by RAB40B expression — LUSC

Box plot of RNA5SP509 in RAB40B-low vs RAB40B-high samples in LUSC.

Explore this box plot interactively →

Exploration