RAB40B

Across TCGA pan-cancer cohorts, RAB40B RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RAB40B data layer compared with 6 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RAB40B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAB40B expression acts as an unfavorable survival marker, although some lineages such as MESO and SKCM show a favorable association.

KIRP, MESO, and BLCA are the cancer types where RAB40B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	All	0.858	0.955	<.001	106	view →
MESO	DFS	Tertile	All	0.580	0.308	<.001	93	view →
BLCA	OS	Quartile	IV	0.247	0.782	.005	55	view →
SKCM	DFS	Tertile	II,III,IV	0.644	0.483	.001	44	view →
KIRC	OS	Median	All	0.710	0.559	<.001	41	view →
ESCA	DFS	Median	All	0.450	0.930	.003	21	view →
ACC	DFS	Tertile	II,III,IV	0.538	0.978	.002	20	view →
READ	DFS	Median	IV	0.374	0.845	.002	18	view →
LIHC	DFS	Quartile	All	0.237	0.445	.001	18	view →
STAD	OS	Median	IV	0.157	0.652	.012	15	view →
LUSC	DFS	Quartile	All	0.455	0.289	.014	14	view →
OV	OS	Quartile	III,IV	0.897	0.785	.021	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RAB40B–KIRP (DFS)

Open the KIRP breakdown →