RAB40A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RAB40A mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RAB40A-associated genes across cancer lineages are ADIG and OR4F15. Each is linked with RAB40A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB40A-to-partner and partner-to-RAB40A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADIG grouped by RAB40A-low versus RAB40A-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB40A→partner) and Y-score (partner→RAB40A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCADIG →+0.065+5.029<.001.00631
LUNG_SCLCOR4F15 →+0.029+5.029<.001.00631
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ADIG by RAB40A expression — LUNG_SCLC

Box plot of ADIG in RAB40A-low vs RAB40A-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration