RAB3IP

Across TCGA patient cohorts, RAB3IP mutation is significantly associated with the RNA expression of many other genes, with 1,582 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB3IP-associated genes across cancer lineages are RNA5SP457, MIR7155, and MIR6085. Each is linked with RAB3IP in more than 2 cancer types. Because this analysis shows association rather than direction, both RAB3IP-to-partner and partner-to-RAB3IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP457 grouped by RAB3IP-low versus RAB3IP-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB3IP→partner) and Y-score (partner→RAB3IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNA5SP457 →	+0.461	+3.792	.008	.007	3	3
LUSC	MIR7155 →	+0.722	+2.834	<.001	.009	3	3
LIHC	MIR6085 →	+0.582	+5.447	<.001	.005	3	2
LIHC	RN7SKP116 →	+0.173	+5.878	<.001	.002	3	2
UCEC	ZMYND19 →	+0.376	+2.280	.002	.001	3	2
SKCM	GOLGA2 →	+0.448	+2.166	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,582 associations by consensus.

RNA5SP457 by RAB3IP expression — COAD

Explore this box plot interactively →