RAB3IP

Across TCGA pan-cancer cohorts, RAB3IP RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of RAB3IP’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RAB3IP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RAB3IP is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

BLCA, STAD, and HNSC are the cancer types where RAB3IP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAB3IP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	+1.588	<.001	11	view →
STAD	Female	All	+1.442	<.001	9	view →
HNSC	Male	IV	+1.231	<.001	8	view →
LIHC	All	II,III,IV	+0.740	<.001	8	view →
KIRC	Male	All	−0.582	.002	8	view →
KICH	All	II,III,IV	−1.101	<.001	7	view →
THCA	All	All	−0.289	<.001	7	view →
BRCA	All	III,IV	+0.932	<.001	6	view →
UCEC	All	All	+0.848	<.001	6	view →
ESCA	All	All	+0.926	.002	5	view →
COAD	Male	All	+0.473	<.001	4	view →
CHOL	Female	All	+2.580	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

RAB3IP–BLCA

Open the BLCA breakdown →