RAB3GAP1

Across TCGA pan-cancer cohorts, RAB3GAP1 Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated RAB3GAP1 data layer compared with 29 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher RAB3GAP1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RAB3GAP1 expression acts as an unfavorable survival marker.

OV, SKCM, and KIRC are the cancer types where RAB3GAP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.308	0.691	.033	18	view →
SKCM	OS	Median	III,IV	0.251	0.729	<.001	11	view →
KIRC	OS	Median	All	0.182	0.811	.004	9	view →
KIRP	OS	Median	All	0.118	0.688	.007	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
UCEC	OS	Median	IV	0.506	0.767	.016	6	view →
HNSC	OS	Median	All	0.151	0.685	.007	3	view →
LUAD	DFS	Median	All	0.213	0.676	.030	3	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RAB3GAP1–OV (OS)

Open the OV breakdown →