RAB3GAP1

Across TCGA pan-cancer cohorts, RAB3GAP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RAB3GAP1 data layer compared with 29 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RAB3GAP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RAB3GAP1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

LUAD, HNSC, and PDAC are the cancer types where RAB3GAP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.615	0.950	.004	6	view →
HNSC	OS	Median	IV	0.833	0.635	.026	5	view →
PDAC	OS	Median	IV	0.491	0.836	.024	5	view →
CCRCC	DFS	Median	III,IV	0.558	0.778	.014	3	view →
LSCC	DFS	Tertile	II,III,IV	0.476	0.804	.028	3	view →
UCEC	OS	Median	All	0.964	0.857	.034	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RAB3GAP1–LUAD (OS)

Open the LUAD breakdown →