RAB3GAP1

Across TCGA patient cohorts, RAB3GAP1 mutation is significantly associated with the RNA expression of many other genes, with 2,722 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB3GAP1-associated genes across cancer lineages are DCTPP1, CUEDC1, and RPL23AP82. Each is linked with RAB3GAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB3GAP1-to-partner and partner-to-RAB3GAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCTPP1 grouped by RAB3GAP1-low versus RAB3GAP1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB3GAP1→partner) and Y-score (partner→RAB3GAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	DCTPP1 →	+0.432	+2.851	.006	.001	3	2
SKCM	CUEDC1 →	+0.601	+3.372	<.001	.004	3	2
SKCM	RPL23AP82 →	+0.547	+3.232	.002	.008	3	2
SKCM	PCNX3 →	+0.419	+3.412	.008	.004	3	2
SKCM	AKT1S1 →	+0.455	+3.195	.001	.009	3	2
SKCM	CENPBD1P1 →	+0.472	+3.604	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,722 associations by consensus.

DCTPP1 by RAB3GAP1 expression — SKCM

Explore this box plot interactively →