RAB3D

Across TCGA patient cohorts, RAB3D mutation is significantly associated with the RNA expression of many other genes, with 224 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB3D-associated genes across cancer lineages are RNU6-548P, MIR26A1, and PHKG1P1. Each is linked with RAB3D in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB3D-to-partner and partner-to-RAB3D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-548P grouped by RAB3D-low versus RAB3D-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB3D→partner) and Y-score (partner→RAB3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-548P →	+0.604	+2.542	.005	.007	3	2
CESC	MIR26A1 →	+0.731	+5.306	<.001	.006	3	1
CESC	PHKG1P1 →	+0.070	+6.144	<.001	.001	3	1
CESC	LINC00708 →	+0.045	+5.418	<.001	.005	3	1
CESC	RNU7-63P →	+0.646	+5.306	<.001	.006	3	1
CESC	RPL32P30 →	+0.284	+5.010	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 224 associations by consensus.

RNU6-548P by RAB3D expression — UCEC

Explore this box plot interactively →