RAB3C

Across TCGA cell cohorts, RAB3C RNA expression is significantly associated with the go_rna of many other GO terms, with 1,680 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAB3C-associated GO terms across cancer lineages are Engulfment of apoptotic cell, Protein activation cascade, and Amelogenesis. Each is linked with RAB3C in more than 4 cancer types. Because this analysis shows association rather than direction, both RAB3C-to-partner and partner-to-RAB3C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Engulfment of apoptotic cell grouped by RAB3C-low versus RAB3C-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB3C→partner) and Y-score (partner→RAB3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Engulfment of apoptotic cell →	-0.096	-0.811	.003	.007	3	5
CNS	Protein activation cascade →	-0.183	-0.608	<.001	.009	3	4
CNS	Amelogenesis →	-0.166	-0.365	<.001	.004	3	4
LUNG_SCLC	Regulation of isotype switching to IgE isotypes →	-0.757	-2.824	.005	<.001	3	4
LUNG_SCLC	Positive regulation of isotype switching to IgE isotypes →	-0.757	-2.824	.005	<.001	3	4
LUNG_SCLC	tRNA metabolic process →	+0.052	+2.065	.002	.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,680 associations by consensus.

Engulfment of apoptotic cell by RAB3C expression — BLOOD_Leukemia

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